U.S. Full Prescribing Information, including Boxed WARNING Medication Guide
U.S. Healthcare Professionals Indication

Indication

CAMZYOS is a prescription medicine used to treat adults with symptomatic obstructive hypertrophic cardiomyopathy (HCM). CAMZYOS may improve your symptoms and your ability to be active.

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WHAT IS OBSTRUCTIVE
HYPERTROPHIC CARDIOMYOPATHY (HCM)?

Obstructive HCM is the most common type of HCM—a condition that can affect the function of your heart.

HCM causes the heart muscle wall to thicken and stiffen, making it harder for the heart to fill with blood. When HCM causes the heart muscle to get so thick that it blocks or reduces blood flow from the heart to the rest of the body, it’s called obstructive HCM. Obstructive HCM is also referred to as HoCM (short for hypertrophic obstructive cardiomyopathy), and you may have heard this term in discussions with your doctor.

Obstructive HCM makes it difficult for the heart muscle to relax, so the heart must work harder and use more energy. When you have symptoms with obstructive HCM, it’s called symptomatic obstructive HCM. These symptoms can increase with physical exertion and worsen over time.

Did you know

HCM is a heart disease that can be inherited, which means it may run in your family due to genetics. In fact, it’s estimated that HCM impacts between 1 in 200* and 1 in 500 people.

*The 2015 Semsarian publication identified that the prevalence of HCM could be as high as 1 in 200.

†The 1995 CARDIA study—a multicenter, US-population–based echocardiography study of 4111 subjects (aged 23-35) identified the prevalence of HCM as 1 in 500 in the general population.

A healthy heart, a heart with hypertrophic cardiomyopathy (HCM), and a heart with obstructive hypertrophic cardiomyopathy (oHCM) A healthy heart, a heart with hypertrophic cardiomyopathy (HCM), and a heart with obstructive hypertrophic cardiomyopathy (oHCM)

The majority of people with HCM have been diagnosed with obstructive HCM.

Common symptoms can include:

Shortness of breath

Rapid heartbeat

Chest pain

Feeling light-headed

Fainting

Fatigue

People with obstructive HCM may experience additional symptoms that are not shown here.

Talk to your doctor if you have been diagnosed with obstructive HCM and are experiencing any of the symptoms above.

Download these tools to help you discuss your symptoms.

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