THE FIRST AND ONLY
FDA-APPROVED
TREATMENT OF ITS KIND

CAMZYOS® is a cardiac myosin inhibitor that targets
the source of symptomatic obstructive HCM.

Stephanie, a symptomatic obstructive HCM patient, was compensated for her time.

CAMZYOS is a prescription medicine used to treat adults with symptomatic obstructive HCM and may improve both your symptoms and your ability to be active. If you're limiting your activities in hopes of avoiding oHCM symptoms, you deserve an opportunity to get back to those activities you love. Talk to your doctor and ask if CAMZYOS may be right for you.

CAMZYOS Works Differently

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Watch video about how Rx CAMZYOS® (mavacamten) works

See how CAMZYOS works to target the source of obstructive HCM deep within the heart muscle.

To understand how CAMZYOS works, it's helpful to know how certain proteins help contribute to the pumping action of your heart:

Legend
Connected myosin protein, resting myosin protein, actin protein, and Rx CAMZYOS® binding to myosin
Normal heart
Normal heart

Two proteins in the heart muscle, called myosin and actin, contribute to your heart pumping by connecting (making the heart contract) and releasing (allowing the heart to relax).

Heart with obstructive HCM
Heart with obstructive hypertrophic cardiomyopathy (oHCM)

In obstructive HCM, myosin and actin form too many connections with each other, causing the heart to contract too much, which can make it difficult for it to relax.

How CAMZYOS works in a heart with obstructive HCM
Heart with obstructive hypertrophic cardiomyopathy (oHCM) with Rx CAMZYOS® (mavacamten)

CAMZYOS binds to myosin so that it “lets go” of actin, reducing the excessive connections between them. This action allows your heart muscle to relax more.

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Why is it important to know how CAMZYOS works?

In people with symptomatic obstructive HCM, reducing the connections between myosin and actin
may decrease the obstruction and improve heart function (how the heart relaxes and fills with blood).

To learn more about CAMZYOS, please see U.S. Full Prescribing Information, including Boxed WARNING and Medication Guide.



© 2025 MyoKardia, Inc., a Bristol Myers Squibb company.
CAMZYOS® and the CAMZYOS and MyCAMZYOS Logos are trademarks of MyoKardia, Inc.
This website is intended for U.S. residents 18 years of age or older.
3500-US-2400785 03/25

Cammie
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To begin with, there are a few things I need to tell you. Please use the scroll bar on the upper right to view all of the information and then press continue. All conversations are recorded for quality purposes. Support is available for customers in the U.S. The information you provide will be governed by our privacy policy. I cannot provide medical advice. Your healthcare provider is the best source of medical information. Some important safety information to know is: CAMZYOS® (mavacamten) may cause serious side effects, including heart failure, a condition where the heart cannot pump with enough force. Heart failure is a serious condition that can lead to death. You must have echocardiograms before you take your first dose and during your treatment with CAMZYOS to help your healthcare provider understand how your heart is responding to CAMZYOS. People who develop a serious infection or irregular heartbeat have a greater risk of heart failure during treatment with CAMZYOS. Tell your healthcare provider or get medical help right away if you develop new or worsening shortness of breath, chest pain, fatigue, swelling in your legs, or a racing sensation in your heart (palpitations) or rapid weight gain. Please click here for full Important Safety Information, including Boxed WARNING, for CAMZYOS.
Please see the full U.S. Prescribing Information, including Boxed WARNING, and the Medication Guide for CAMZYOS. For your privacy protection, please do not share personal information about another person.
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