U.S. Full Prescribing Information, including Boxed WARNING Medication Guide
U.S. Healthcare Professionals Indication

Indication

CAMZYOS is a prescription medicine
used to treat adults with symptomatic
obstructive hypertrophic cardiomyopathy
(HCM). CAMZYOS may improve your
symptoms and your ability to be active.

It is not known if CAMZYOS is safe and effective in children.

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Before starting on treatment, your cardiologist will help you understand the potential benefits and side effects of CAMZYOS®. It’s also important to understand what safety precautions you will need to take before and during your treatment.

CAMZYOS REMS Program


In some patients, CAMZYOS can cause the heart to become too relaxed, increasing the risk of heart failure. Because of this risk, CAMZYOS is only available through the CAMZYOS REMS program, which is required by the FDA to monitor the safe use of the medication.

Your doctor will review the CAMZYOS REMS brochure with you and explain your participation in the program.

Learn More

Additional Precautions

Your doctor needs to know the answers to these important questions before and during treatment with CAMZYOS:

Do you have other medical conditions? Are you pregnant or breastfeeding, or do you plan to become pregnant or breastfeed?

CAMZYOS may harm your unborn baby. Tell your healthcare provider right away if you become pregnant or think you may be pregnant during treatment with CAMZYOS. You may also report your pregnancy by calling the Bristol Myers Squibb reporting line at 1-800-721-5072 or at www.bms.com.

If you are a female and able to become pregnant:

  • Your healthcare provider will do a pregnancy test before you start treatment with CAMZYOS
  • You should use effective birth control (contraception) during treatment with CAMZYOS and for 4 months after your final dose of CAMZYOS.
  • CAMZYOS may reduce how well hormonal birth control works. Talk to your healthcare provider about the use of effective forms of birth control during treatment with CAMZYOS

It is not known if CAMZYOS passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby if you take CAMZYOS.

Important to know

Before and during your treatment with CAMZYOS, tell your healthcare provider about all the medicines you are taking, plan to take, or plan to stop taking. Click here to learn more.

Tell your healthcare provider right away

if you experience new or worsening shortness of breath, chest pain, fatigue, swelling in your legs, a racing sensation of your heart (palpitations), or rapid weight gain.

Side Effects

If you and your doctor are considering CAMZYOS, it’s important to know the
answers to these questions:

What are the serious side effects of CAMZYOS?

A serious side effect is a side effect that can sometimes be life-threatening and lead to death.

CAMZYOS may cause serious side effects, including heart failure (a condition where the heart cannot pump with enough force).

Get medical help right away if you experience new or worsening symptoms, including:

  • Shortness of breath
  • Chest pain
  • Fatigue
  • Racing heart (palpitations)
  • Leg swelling
  • Rapid weight gain

What are the most common side effects?

The most common side effects of CAMZYOS include dizziness and fainting (syncope).

  • Tell your healthcare provider if you have any side effect that bothers you or that does not go away
  • These are not all of the possible side effects of CAMZYOS
  • Talk to your healthcare provider for more information about side effects. You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects to Bristol Myers Squibb at 1-800-721-5072

For more information, please see the U.S. Full Prescribing Information, including Boxed WARNING and Medication Guide for CAMZYOS. Talk to your healthcare provider for more information about this medication.

Learn About MyCAMZYOS Patient Support